Histone deacetylase inhibitor thailandepsin-A activates Notch signaling and suppresses neuroendocrine cancer cell growth in vivo

Novel therapies for neuroendocrine (NE) cancers are desperately needed as they frequently present as metastatic disease and cause debilitating symptoms by secreting excessive hormones. Induction of Notch isoforms has a tumor suppressive effect in NE cancer cell lines, and we have observed that histo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Jang, Samuel, Janssen, Andrew, Aburjania, Zviadi, Robers, Matthew B., Harrison, April, Dammalapati, Ajitha, Cheng, Yi-Qiang, Chen, Herbert, Jaskula-Sztul, Renata
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2017
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642598/
https://ncbi.nlm.nih.gov/pubmed/29050323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19993
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