Histone deacetylase inhibitor thailandepsin-A activates Notch signaling and suppresses neuroendocrine cancer cell growth in vivo

Novel therapies for neuroendocrine (NE) cancers are desperately needed as they frequently present as metastatic disease and cause debilitating symptoms by secreting excessive hormones. Induction of Notch isoforms has a tumor suppressive effect in NE cancer cell lines, and we have observed that histo...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Jang, Samuel, Janssen, Andrew, Aburjania, Zviadi, Robers, Matthew B., Harrison, April, Dammalapati, Ajitha, Cheng, Yi-Qiang, Chen, Herbert, Jaskula-Sztul, Renata
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642598/
https://ncbi.nlm.nih.gov/pubmed/29050323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19993
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