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Histone deacetylase inhibitor thailandepsin-A activates Notch signaling and suppresses neuroendocrine cancer cell growth in vivo

Novel therapies for neuroendocrine (NE) cancers are desperately needed as they frequently present as metastatic disease and cause debilitating symptoms by secreting excessive hormones. Induction of Notch isoforms has a tumor suppressive effect in NE cancer cell lines, and we have observed that histo...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncotarget
Main Authors: Jang, Samuel, Janssen, Andrew, Aburjania, Zviadi, Robers, Matthew B., Harrison, April, Dammalapati, Ajitha, Cheng, Yi-Qiang, Chen, Herbert, Jaskula-Sztul, Renata
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals LLC 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5642598/
https://ncbi.nlm.nih.gov/pubmed/29050323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19993
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