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Thiocoraline alters neuroendocrine phenotype and activates the Notch pathway in MTC-TT cell line

Medullary thyroid cancer (MTC) is an aggressive neuroendocrine tumor (NET). Previous research has shown that activation of Notch signaling has a tumor suppressor role in NETs. The potential therapeutic effect of thiocoraline on the activation of the Notch pathway in an MTC cell line (TT) was investi...

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Detalhes bibliográficos
Main Authors: Tesfazghi, Sara, Eide, Jacob, Dammalapati, Ajitha, Korlesky, Colin, Wyche, Thomas P, Bugni, Tim S, Chen, Herbert, Jaskula-Sztul, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892805/
https://ncbi.nlm.nih.gov/pubmed/24403239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.118
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