Functional Analysis and Transcriptomic Profiling of iPSC-derived Macrophages and Their Application in Modeling Mendelian Disease

RATIONALE: An efficient and reproducible source of genotype-specific human macrophages is essential for study of human macrophage biology and related diseases. OBJECTIVE: To perform integrated functional and transcriptome analyses of human induced pluripotent stem cell-derived macrophages (IPSDM) an...

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Publicado no:Circ Res
Main Authors: Zhang, Hanrui, Xue, Chenyi, Shah, Rhia, Bermingham, Kate, Hinkle, Christine C., Li, Wenjun, Rodrigues, Amrith, Tabita-Martinez, Jennifer, Millar, John S., Cuchel, Marina, Pashos, Evanthia E., Liu, Ying, Yan, Ruilan, Yang, Wenli, Gosai, Sager J., VanDorn, Daniel, Chou, Stella T., Gregory, Brian D., Morrisey, Edward E., Li, Mingyao, Rader, Daniel J., Reilly, Muredach P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565503/
https://ncbi.nlm.nih.gov/pubmed/25904599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.305860
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