Protracted dormancy of pre-leukemic stem cells

Cancer stem cells can escape therapeutic killing by adopting a quiescent or dormant state. The reversibility of this condition provides the potential for later recurrence or relapse, potentially many years later. We describe the genomics of a rare case of childhood BCR-ABL1-positive, B-cell precurso...

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Publicado en:Leukemia
Autores principales: Ford, A M, Mansur, M B, Furness, C L, van Delft, F W, Okamura, J, Suzuki, T, Kobayashi, H, Kaneko, Y, Greaves, M
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564945/
https://ncbi.nlm.nih.gov/pubmed/26017033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2015.132
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