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Response and Acquired Resistance to Everolimus in Anaplastic Thyroid Cancer
Everolimus, an inhibitor of the mammalian target of rapamycin (mTOR), is effective in treating tumors harboring alterations in the mTOR pathway. Mechanisms of resistance to everolimus remain undefined. Resistance developed in a patient with metastatic anaplastic thyroid carcinoma after an extraordin...
Shranjeno v:
| izdano v: | N Engl J Med |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4564868/ https://ncbi.nlm.nih.gov/pubmed/25295501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1403352 |
| Oznake: |
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