Response and Acquired Resistance to Everolimus in Anaplastic Thyroid Cancer

Everolimus, an inhibitor of the mammalian target of rapamycin (mTOR), is effective in treating tumors harboring alterations in the mTOR pathway. Mechanisms of resistance to everolimus remain undefined. Resistance developed in a patient with metastatic anaplastic thyroid carcinoma after an extraordin...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:N Engl J Med
Main Authors: Wagle, Nikhil, Grabiner, Brian C., Van Allen, Eliezer M., Amin-Mansour, Ali, Taylor-Weiner, Amaro, Rosenberg, Mara, Gray, Nathanael, Barletta, Justine A., Guo, Yanan, Swanson, Scott J., Ruan, Daniel T., Hanna, Glenn J., Haddad, Robert I., Getz, Gad, Kwiatkowski, David J., Carter, Scott L., Sabatini, David M., Jänne, Pasi A., Garraway, Levi A., Lorch, Jochen H.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564868/
https://ncbi.nlm.nih.gov/pubmed/25295501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1403352
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki