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Higher Sensitivity of Foxp3(+) Treg Compared to Foxp3(-) Conventional T Cells to TCR-Independent Signals for CD69 Induction

T lymphocytes elicit specific responses after recognizing cognate antigen. However, antigen-experienced T cells can also respond to non-cognate stimuli, such as cytokines. CD4(+) Foxp3(+) regulatory T cells (Treg) exhibit an antigen-experienced-like phenotype. Treg can regulate T cell responses in a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bremser, Anna, Brack, Maria, Izcue, Ana
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564208/
https://ncbi.nlm.nih.gov/pubmed/26352149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137393
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