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BACOM2.0 facilitates absolute normalization and quantification of somatic copy number alterations in heterogeneous tumor
Most published copy number datasets on solid tumors were obtained from specimens comprised of mixed cell populations, for which the varying tumor-stroma proportions are unknown or unreported. The inability to correct for signal mixing represents a major limitation on the use of these datasets for su...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4563570/ https://ncbi.nlm.nih.gov/pubmed/26350498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13955 |
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