Local and Systemic IKKε and NF-κB Signaling Associated with Sjögren's Syndrome Immunopathogenesis

The activated NF-κB signaling pathway plays an important role in pathogenesis of primary Sjögren's syndrome (pSS). The inhibitor of κB (IκB) kinase (IKK) family such as IKKα, IKKβ, IKKγ, and IKKε, is required for this signaling. Our aim was to investigate the role of IKKα/β/γ/ε in patients with...

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Udgivet i:J Immunol Res
Main Authors: Chen, Weiqian, Lin, Jin, Cao, Heng, Xu, Danyi, Xu, Bei, Xu, Liqin, Yue, Lihuan, Sun, Chuanyin, Wu, Guolin, Qian, Wenbin
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563092/
https://ncbi.nlm.nih.gov/pubmed/26380323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/534648
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