Local and Systemic IKKε and NF-κB Signaling Associated with Sjögren's Syndrome Immunopathogenesis

The activated NF-κB signaling pathway plays an important role in pathogenesis of primary Sjögren's syndrome (pSS). The inhibitor of κB (IκB) kinase (IKK) family such as IKKα, IKKβ, IKKγ, and IKKε, is required for this signaling. Our aim was to investigate the role of IKKα/β/γ/ε in patients with...

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Bibliografski detalji
Izdano u:J Immunol Res
Glavni autori: Chen, Weiqian, Lin, Jin, Cao, Heng, Xu, Danyi, Xu, Bei, Xu, Liqin, Yue, Lihuan, Sun, Chuanyin, Wu, Guolin, Qian, Wenbin
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563092/
https://ncbi.nlm.nih.gov/pubmed/26380323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/534648
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