Local and Systemic IKKε and NF-κB Signaling Associated with Sjögren's Syndrome Immunopathogenesis

The activated NF-κB signaling pathway plays an important role in pathogenesis of primary Sjögren's syndrome (pSS). The inhibitor of κB (IκB) kinase (IKK) family such as IKKα, IKKβ, IKKγ, and IKKε, is required for this signaling. Our aim was to investigate the role of IKKα/β/γ/ε in patients with...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Chen, Weiqian, Lin, Jin, Cao, Heng, Xu, Danyi, Xu, Bei, Xu, Liqin, Yue, Lihuan, Sun, Chuanyin, Wu, Guolin, Qian, Wenbin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563092/
https://ncbi.nlm.nih.gov/pubmed/26380323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/534648
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