Genetic deficit of K(Ca)3.1 channels protects against pulmonary circulatory collapse induced by TRPV4 channel activation

BACKGROUND AND PURPOSE: The intermediate conductance calcium/calmodulin-regulated K(+) channel K(Ca)3.1 produces hyperpolarizing K(+) currents that counteract depolarizing currents carried by transient receptor potential (TRP) channels, and provide the electrochemical driving force for Cl(−) and flu...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Wandall-Frostholm, Christine, Dalsgaard, Thomas, Bajoriūnas, Vytis, Oliván-Viguera, Aida, Sadda, Veeruanjaneyulu, Beck, Lilliana, Mogensen, Susie, Stankevicius, Edgaras, Simonsen, Ulf, Köhler, Ralf
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562510/
https://ncbi.nlm.nih.gov/pubmed/26102209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13234
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