Extracellular l-arginine Enhances Relaxations Induced by Opening of Calcium-Activated SKCa Channels in Porcine Retinal Arteriole

We investigated whether the substrate for nitric oxide (NO) production, extracellular l-arginine, contributes to relaxations induced by activating small (SKCa) conductance Ca(2+)-activated potassium channels. In endothelial cells, acetylcholine increased (3)H-l-arginine uptake, while blocking the SK...

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Publicado en:Int J Mol Sci
Autores principales: Simonsen, Ulf, Winther, Anna K., Oliván-Viguera, Aida, Comerma-Steffensen, Simon, Köhler, Ralf, Bek, Toke
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6515554/
https://ncbi.nlm.nih.gov/pubmed/31027156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20082032
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