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Pulmonary Hypertension in Wild Type Mice and Animals with Genetic Deficit in K(Ca)2.3 and K(Ca)3.1 Channels

OBJECTIVE: In vascular biology, endothelial K(Ca)2.3 and K(Ca)3.1 channels contribute to arterial blood pressure regulation by producing membrane hyperpolarization and smooth muscle relaxation. The role of K(Ca)2.3 and K(Ca)3.1 channels in the pulmonary circulation is not fully established. Using mi...

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Detalhes bibliográficos
Main Authors: Wandall-Frostholm, Christine, Skaarup, Lykke Moran, Sadda, Veeranjaneyulu, Nielsen, Gorm, Hedegaard, Elise Røge, Mogensen, Susie, Köhler, Ralf, Simonsen, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032241/
https://ncbi.nlm.nih.gov/pubmed/24858807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097687
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