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Pulmonary Hypertension in Wild Type Mice and Animals with Genetic Deficit in K(Ca)2.3 and K(Ca)3.1 Channels

OBJECTIVE: In vascular biology, endothelial K(Ca)2.3 and K(Ca)3.1 channels contribute to arterial blood pressure regulation by producing membrane hyperpolarization and smooth muscle relaxation. The role of K(Ca)2.3 and K(Ca)3.1 channels in the pulmonary circulation is not fully established. Using mi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wandall-Frostholm, Christine, Skaarup, Lykke Moran, Sadda, Veeranjaneyulu, Nielsen, Gorm, Hedegaard, Elise Røge, Mogensen, Susie, Köhler, Ralf, Simonsen, Ulf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032241/
https://ncbi.nlm.nih.gov/pubmed/24858807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097687
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