Pulmonary Hypertension in Wild Type Mice and Animals with Genetic Deficit in K(Ca)2.3 and K(Ca)3.1 Channels

OBJECTIVE: In vascular biology, endothelial K(Ca)2.3 and K(Ca)3.1 channels contribute to arterial blood pressure regulation by producing membrane hyperpolarization and smooth muscle relaxation. The role of K(Ca)2.3 and K(Ca)3.1 channels in the pulmonary circulation is not fully established. Using mi...

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Main Authors: Wandall-Frostholm, Christine, Skaarup, Lykke Moran, Sadda, Veeranjaneyulu, Nielsen, Gorm, Hedegaard, Elise Røge, Mogensen, Susie, Köhler, Ralf, Simonsen, Ulf
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032241/
https://ncbi.nlm.nih.gov/pubmed/24858807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097687
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