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Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor

HIV-1 infection depends on effective viral entry mediated by the interaction of its envelope (Env) glycoprotein with specific cell surface receptors. Protective antiviral antibodies generated by passive or active immunization must prevent these interactions. Because the HIV-1 Env is highly variable,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Transl Med
मुख्य लेखकों: Pegu, Amarendra, Yang, Zhi-yong, Boyington, Jeffrey C., Wu, Lan, Ko, Sung-Youl, Schmidt, Stephen D., McKee, Krisha, Kong, Wing-Pui, Shi, Wei, Chen, Xuejun, Todd, John-Paul, Letvin, Norman L., Huang, Jinghe, Nason, Martha C., Hoxie, James A., Kwong, Peter D., Connors, Mark, Rao, Srinivas S., Mascola, John R., Nabel, Gary J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562469/
https://ncbi.nlm.nih.gov/pubmed/24990883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008992
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