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Bicc1 Polymerization Regulates the Localization and Silencing of Bound mRNA
Loss of the RNA-binding protein Bicaudal-C (Bicc1) provokes renal and pancreatic cysts as well as ectopic Wnt/β-catenin signaling during visceral left-right patterning. Renal cysts are linked to defective silencing of Bicc1 target mRNAs, including adenylate cyclase 6 (AC6). RNA binding of Bicc1 is m...
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| Izdano u: | Mol Cell Biol |
|---|---|
| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4561730/ https://ncbi.nlm.nih.gov/pubmed/26217012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00341-15 |
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