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Ca(2+) toxicity due to reverse Na(+)/Ca(2+) exchange contributes to degeneration of neurites of DRG neurons induced by a neuropathy-associated Nav1.7 mutation
Gain-of-function missense mutations in voltage-gated sodium channel Nav1.7 have been linked to small-fiber neuropathy, which is characterized by burning pain, dysautonomia and a loss of intraepidermal nerve fibers. However, the mechanistic cascades linking Nav1.7 mutations to axonal degeneration are...
में बचाया:
| में प्रकाशित: | J Neurophysiol |
|---|---|
| मुख्य लेखकों: | , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Physiological Society
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4561630/ https://ncbi.nlm.nih.gov/pubmed/26156380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00195.2015 |
| टैग : |
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