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A painful neuropathy-associated Nav1.7 mutant leads to time-dependent degeneration of small-diameter axons associated with intracellular Ca(2+) dysregulation and decrease in ATP levels
Small fiber neuropathy is a painful sensory nervous system disorder characterized by damage to unmyelinated C- and thinly myelinated Aδ- nerve fibers, clinically manifested by burning pain in the distal extremities and dysautonomia. The clinical onset in adulthood suggests a time-dependent process....
Enregistré dans:
| Publié dans: | Mol Pain |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
SAGE Publications
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5102167/ https://ncbi.nlm.nih.gov/pubmed/27821467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916674472 |
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