SETDB1 modulates PRC2 activity at developmental genes independently of H3K9 trimethylation in mouse ES cells

SETDB1, a histone methyltransferase responsible for methylation of histone H3 lysine 9 (H3K9), is involved in maintenance of embryonic stem (ES) cells and early embryonic development of the mouse. However, how SETDB1 regulates gene expression during development is largely unknown. Here, we character...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Genome Res
Main Authors: Fei, Qi, Yang, Xiaoqin, Jiang, Hua, Wang, Qian, Yu, Yanyan, Yu, Yiling, Yi, Wei, Zhou, Shaolian, Chen, Taiping, Lu, Chris, Atadja, Peter, Liu, Xiaole Shirley, Li, En, Zhang, Yong, Shou, Jianyong
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2015
נושאים:
Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561491/
https://ncbi.nlm.nih.gov/pubmed/26160163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.177576.114
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