SETDB1 modulates PRC2 activity at developmental genes independently of H3K9 trimethylation in mouse ES cells

SETDB1, a histone methyltransferase responsible for methylation of histone H3 lysine 9 (H3K9), is involved in maintenance of embryonic stem (ES) cells and early embryonic development of the mouse. However, how SETDB1 regulates gene expression during development is largely unknown. Here, we character...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Fei, Qi, Yang, Xiaoqin, Jiang, Hua, Wang, Qian, Yu, Yanyan, Yu, Yiling, Yi, Wei, Zhou, Shaolian, Chen, Taiping, Lu, Chris, Atadja, Peter, Liu, Xiaole Shirley, Li, En, Zhang, Yong, Shou, Jianyong
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561491/
https://ncbi.nlm.nih.gov/pubmed/26160163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.177576.114
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