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SETDB1 modulates PRC2 activity at developmental genes independently of H3K9 trimethylation in mouse ES cells
SETDB1, a histone methyltransferase responsible for methylation of histone H3 lysine 9 (H3K9), is involved in maintenance of embryonic stem (ES) cells and early embryonic development of the mouse. However, how SETDB1 regulates gene expression during development is largely unknown. Here, we character...
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| Publicado en: | Genome Res |
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| Autores principales: | , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4561491/ https://ncbi.nlm.nih.gov/pubmed/26160163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.177576.114 |
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