Crosslink Mapping at Amino Acid-Base Resolution Reveals the Path of Scrunched DNA in Initial Transcribing Complexes

RNA polymerase binds tightly to DNA to recognize promoters with high specificity but then releases these contacts during the initial stage of transcription. We report a site-specific crosslinking approach to map the DNA path in bacterial transcription intermediates at amino acid and nucleotide resol...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Winkelman, Jared T., Winkelman, Bradford T., Boyce, Julian, Maloney, Michael F., Chen, Albert Y., Ross, Wilma, Gourse, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561013/
https://ncbi.nlm.nih.gov/pubmed/26257284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.06.037
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados