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Open complex scrunching before nucleotide addition accounts for the unusual transcription start site of E. coli ribosomal RNA promoters

Most Escherichia coli promoters initiate transcription with a purine 7 or 8 nt downstream from the –10 hexamer, but some promoters, including the ribosomal RNA promoter rrnB P1, start 9 nt from the –10 element. We identified promoter and RNA polymerase determinants of this noncanonical rrnB P1 start...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Winkelman, Jared T., Chandrangsu, Pete, Ross, Wilma, Gourse, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822585/
https://ncbi.nlm.nih.gov/pubmed/26976590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522159113
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