TAF11 assembles RISC loading complex to enhance RNAi efficiency

Assembly of the RNA-induced silencing complex (RISC) requires formation of the RISC loading complex (RLC), which contains Dicer-2(Dcr-2)-R2D2 complex and recruits duplex siRNA to Ago2 in Drosophila melanogaster. However, the precise composition and action mechanism of Drosophila RLC remain unclear....

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Bibliografiska uppgifter
I publikationen:Mol Cell
Huvudupphovsmän: Liang, Chunyang, Wang, Yibing, Murota, Yukiko, Liu, Xiang, Smith, Dean, Siomi, Mikiko C., Liu, Qinghua
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560963/
https://ncbi.nlm.nih.gov/pubmed/26257286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.07.006
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