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TAF11 assembles RISC loading complex to enhance RNAi efficiency
Assembly of the RNA-induced silencing complex (RISC) requires formation of the RISC loading complex (RLC), which contains Dicer-2(Dcr-2)-R2D2 complex and recruits duplex siRNA to Ago2 in Drosophila melanogaster. However, the precise composition and action mechanism of Drosophila RLC remain unclear....
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| Pubblicato in: | Mol Cell |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4560963/ https://ncbi.nlm.nih.gov/pubmed/26257286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.07.006 |
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