Human cytomegalovirus in a SCID-hu mouse: thymic epithelial cells are prominent targets of viral replication.

Animal models of human cytomegalovirus (CMV) infections have not been available to study pathogenesis or to evaluate antiviral drugs. Severe combined immunodeficient mice implanted with human fetal tissues (SCID-hu) were found to support CMV replication and may provide a model for this species-speci...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Mocarski, E S, Bonyhadi, M, Salimi, S, McCune, J M, Kaneshima, H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45608/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7678330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.1.104
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