Use of standardized SCID-hu Thy/Liv mouse model for preclinical efficacy testing of anti-human immunodeficiency virus type 1 compounds.

We have developed standardized procedures and practices for infection of SCID-hu Thy/Liv mice with human immunodeficiency virus type 1 for the prophylactic administration of antiviral compounds and for evaluation of the antiviral effect in vivo. Endpoint analyses included quantitation of viral load...

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Detalhes bibliográficos
Main Authors: Rabin, L, Hincenbergs, M, Moreno, M B, Warren, S, Linquist, V, Datema, R, Charpiot, B, Seifert, J, Kaneshima, H, McCune, J M
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC163193/
https://ncbi.nlm.nih.gov/pubmed/8851606
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