Human cytomegalovirus in a SCID-hu mouse: thymic epithelial cells are prominent targets of viral replication.

Animal models of human cytomegalovirus (CMV) infections have not been available to study pathogenesis or to evaluate antiviral drugs. Severe combined immunodeficient mice implanted with human fetal tissues (SCID-hu) were found to support CMV replication and may provide a model for this species-speci...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Mocarski, E S, Bonyhadi, M, Salimi, S, McCune, J M, Kaneshima, H
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1993
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45608/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7678330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.1.104
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