Human cytomegalovirus in a SCID-hu mouse: thymic epithelial cells are prominent targets of viral replication.
Animal models of human cytomegalovirus (CMV) infections have not been available to study pathogenesis or to evaluate antiviral drugs. Severe combined immunodeficient mice implanted with human fetal tissues (SCID-hu) were found to support CMV replication and may provide a model for this species-speci...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1993
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45608/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7678330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.1.104 |
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