Human cytomegalovirus in a SCID-hu mouse: thymic epithelial cells are prominent targets of viral replication.

Animal models of human cytomegalovirus (CMV) infections have not been available to study pathogenesis or to evaluate antiviral drugs. Severe combined immunodeficient mice implanted with human fetal tissues (SCID-hu) were found to support CMV replication and may provide a model for this species-speci...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Mocarski, E S, Bonyhadi, M, Salimi, S, McCune, J M, Kaneshima, H
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1993
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45608/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7678330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.1.104
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