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Regulatory Divergence of Transcript Isoforms in a Mammalian Model System

Phenotypic differences between species are driven by changes in gene expression and, by extension, by modifications in the regulation of the transcriptome. Investigation of mammalian transcriptome divergence has been restricted to analysis of bulk gene expression levels and gene-internal splicing. U...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Leigh-Brown, Sarah, Goncalves, Angela, Thybert, David, Stefflova, Klara, Watt, Stephen, Flicek, Paul, Brazma, Alvis, Marioni, John C., Odom, Duncan T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560434/
https://ncbi.nlm.nih.gov/pubmed/26339903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137367
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