Extensive compensatory cis-trans regulation in the evolution of mouse gene expression

Gene expression levels are thought to diverge primarily via regulatory mutations in trans within species, and in cis between species. To test this hypothesis in mammals we used RNA-sequencing to measure gene expression divergence between C57BL/6J and CAST/EiJ mouse strains and allele-specific expres...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Goncalves, Angela, Leigh-Brown, Sarah, Thybert, David, Stefflova, Klara, Turro, Ernest, Flicek, Paul, Brazma, Alvis, Odom, Duncan T., Marioni, John C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2012
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514667/
https://ncbi.nlm.nih.gov/pubmed/22919075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.142281.112
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