Extended Preclinical Safety, Efficacy and Stability Testing of a Live-attenuated Chikungunya Vaccine Candidate

We recently described a new, live-attenuated vaccine candidate for chikungunya (CHIK) fever, CHIKV/IRES. This vaccine was shown to be well attenuated, immunogenic and efficacious in protecting against CHIK virus (CHIKV) challenge of mice and nonhuman primates. To further evaluate its preclinical saf...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Negl Trop Dis
Prif Awduron: Plante, Kenneth S, Rossi, Shannan L., Bergren, Nicholas A., Seymour, Robert L., Weaver, Scott C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560411/
https://ncbi.nlm.nih.gov/pubmed/26340754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004007
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