Novel Chikungunya Vaccine Candidate with an IRES-Based Attenuation and Host Range Alteration Mechanism

Chikungunya virus (CHIKV) is a reemerging mosquito-borne pathogen that has recently caused devastating urban epidemics of severe and sometimes chronic arthralgia. As with most other mosquito-borne viral diseases, control relies on reducing mosquito populations and their contact with people, which ha...

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Hlavní autoři: Plante, Kenneth, Wang, Eryu, Partidos, Charalambos D., Weger, James, Gorchakov, Rodion, Tsetsarkin, Konstantin, Borland, Erin M., Powers, Ann M., Seymour, Robert, Stinchcomb, Dan T., Osorio, Jorge E., Frolov, Ilya, Weaver, Scott C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145802/
https://ncbi.nlm.nih.gov/pubmed/21829348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002142
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