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A vaccine candidate for eastern equine encephalitis virus based on IRES-mediated attenuation

To develop an effective vaccine against eastern equine encephalitis (EEE), we engineered a recombinant EEE virus (EEEV) that was attenuated and capable of replicating only in vertebrate cells, an important safety feature for live vaccines against mosquito-borne viruses. The subgenomic promoter was i...

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Bibliografski detalji
Glavni autori: Pandya, Jyotsna, Gorchakov, Rodion, Wang, Eryu, Leal, Grace, Weaver, Scott C.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283035/
https://ncbi.nlm.nih.gov/pubmed/22222869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.12.121
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