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A vaccine candidate for eastern equine encephalitis virus based on IRES-mediated attenuation
To develop an effective vaccine against eastern equine encephalitis (EEE), we engineered a recombinant EEE virus (EEEV) that was attenuated and capable of replicating only in vertebrate cells, an important safety feature for live vaccines against mosquito-borne viruses. The subgenomic promoter was i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3283035/ https://ncbi.nlm.nih.gov/pubmed/22222869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.12.121 |
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