Probing the Attenuation and Protective Efficacy of a Candidate Chikungunya Virus Vaccine in Mice with Compromised Interferon (IFN) Signaling

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes explosive outbreaks of febrile illness associated with rash, and painful arthralgia. The CHIK vaccine strain 181/clone25 (181/25) developed by the United States Army Medical Research Institute of Infectious Diseases (USAMRIID) was...

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Main Authors: Partidos, Charalambos D., Weger, James, Brewoo, Joseph, Seymour, Robert, Borland, Erin M., Ledermann, Jeremy P., Powers, Ann M., Weaver, Scott C., Stinchcomb, Dan T., Osorio, Jorge E.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081687/
https://ncbi.nlm.nih.gov/pubmed/21300099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2011.01.076
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