Interleukin-2 Activity can be Fine-Tuned with Engineered Receptor Signaling Clamps
Interleukin-2 (IL-2) regulates lymphocyte function by signaling through heterodimerization of the IL-2Rβ and γ(c) receptor subunits. IL-2 is of considerable therapeutic interest, but harnessing its actions in a controllable manner remains a challenge. Previously, we have engineered an IL-2 “superkin...
Na minha lista:
| Foilsithe in: | Immunity |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2015
|
| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4560365/ https://ncbi.nlm.nih.gov/pubmed/25992859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.04.018 |
| Clibeanna: |
Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!
|