Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction

Testing of platelet function is central to the cardiovascular phenotyping of genetically modified mice. Traditional platelet function tests have been developed primarily for testing human samples and the volumes required make them highly unsuitable for the testing of mouse platelets. This limits res...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Armstrong, Paul C. J, Kirkby, Nicholas S., Chan, Melissa V., Finsterbusch, Michaela, Hogg, Nancy, Nourshargh, Sussan, Warner, Timothy D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559940/
https://ncbi.nlm.nih.gov/pubmed/26215112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-01-621656
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