Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis

Autophagy is important for maintaining cellular homeostasis, and thus its deficiency is implicated in a broad spectrum of human diseases. Its role in platelet function has only recently been examined. Our biochemical and imaging studies demonstrate that the core autophagy machinery exists in platele...

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Bibliographic Details
Published in:Blood
Main Authors: Ouseph, Madhu M., Huang, Yunjie, Banerjee, Meenakshi, Joshi, Smita, MacDonald, Laura, Zhong, Yu, Liu, Huijuan, Li, Xianting, Xiang, Binggang, Zhang, Guoying, Komatsu, Massaki, Yue, Zhenyu, Li, Zhenyu, Storrie, Brian, Whiteheart, Sidney W., Wang, Qing Jun
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2015
Subjects:
Platelets and Thrombopoiesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559933/
https://ncbi.nlm.nih.gov/pubmed/26209658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-09-598722
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