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The combination of an mTORc1/TORc2 inhibitor with lapatinib is synergistic in bladder cancer in vitro()

OBJECTIVE: To examine the ability of dual mTORc1/c2 inhibitors in conjunction with lapatinib to function in a synergistic manner to inhibit cell proliferation and anchorage-independent growth in bladder cancer cell lines. MATERIALS AND METHODS: We examined patient tumor samples for overexpression of...

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Publicat a:Urol Oncol
Autors principals: Becker, Marie N., Wu, Kevin J., Marlow, Laura A., Kreinest, Pamela A., vonRoemeling, Christina A., Copland, John A., Williams, Christopher R.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559860/
https://ncbi.nlm.nih.gov/pubmed/24054871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urolonc.2013.06.002
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