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XPLN is an endogenous inhibitor of mTORC2

Mammalian target of rapamycin complex 2 (mTORC2) controls a wide range of cellular and developmental processes, but its regulation remains incompletely understood. Through a yeast two-hybrid screen, we have identified XPLN (exchange factor found in platelets, leukemic, and neuronal tissues), a guani...

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Библиографические подробности
Главные авторы: Khanna, Nidhi, Fang, Yimin, Yoon, Mee-Sup, Chen, Jie
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791717/
https://ncbi.nlm.nih.gov/pubmed/24043828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310434110
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