Common variants of the G protein-coupled receptor type 4 are associated with human essential hypertension and predict the blood pressure response to angiotensin receptor blockade

Non-synonymous GRK4 variants, R65L, A142V, and A486V, are associated with essential hypertension in diverse populations. This study replicated the association of GRK4 variants, including GRK4(142V), with human essential hypertension in a Japanese population (n=588; hypertensive, n=486 normotensive c...

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Bibliografske podrobnosti
izdano v:Pharmacogenomics J
Main Authors: Sanada, Hironobu, Yoneda, Minoru, Yatabe, Junichi, Williams, Scott M., Bartlett, Jacquelaine, White, Marquitta J., Gordon, Lindsay N., Felder, Robin A, Eisner, Gilbert M., Armando, Ines, Jose, Pedro A.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559490/
https://ncbi.nlm.nih.gov/pubmed/25732908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2015.6
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