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Effects of Decreased Renal Cortical Expression of G Protein–Coupled Receptor Kinase 4 and Angiotensin Type 1 Receptors in Rats

Abnormalities in renal angiotensin type 1 receptor (AT(1)R), D(1) dopamine receptor (D(1)R) and G protein–coupled receptor kinase 4 (GRK4) are present in polygenic hypertension. Selective renal reduction of AT(1)R expression by intrarenal cortical infusion of antisense oligodeoxynucleotides (As-Odns...

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Detalhes bibliográficos
Main Authors: YATABE, Junichi, SANADA, Hironobu, MIDORIKAWA, Sanae, HASHIMOTO, Shigeatsu, WATANABE, Tsuyoshi, ANDREWS, Peter M., ARMANDO, Ines, WANG, Xiaoyan, FELDER, Robin A., JOSE, Pedro A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731072/
https://ncbi.nlm.nih.gov/pubmed/18957817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1291/hypres.31.1455
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