Hypertension-Related Gene Polymorphisms of G-Protein-Coupled Receptor Kinase 4 Are Associated with NT-proBNP Concentration in Normotensive Healthy Adults

G protein-coupled receptor kinase 4 (GRK4) with activating polymorphisms desensitize the natriuric renal tubular D1 dopamine receptor, and these GRK4 polymorphisms are strongly associated with salt sensitivity and hypertension. Meanwhile, N-terminal pro-B-type natriuretic peptide (NT-proBNP) may be...

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Autores principales: Yatabe, Junichi, Yatabe, Midori S., Yoneda, Minoru, Felder, Robin A., Jose, Pedro A., Sanada, Hironobu
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296214/
https://ncbi.nlm.nih.gov/pubmed/22518293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/806810
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