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Angiotensin II type 1 receptor blocker attenuates the activation of ERK and NADPH oxidase by mechanical strain in mesangial cells in the absence of angiotensin II

It has been reported that mechanical strain activates extracellular signal-regulated protein kinases (ERK) without the involvement of angiotensin II (Ang II) in cardiomyocytes. We examined the effects of mechanical strain on ERK phosphorylation levels in the absence of Ang II using rat mesangial cel...

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Hlavní autoři: Yatabe, Junichi, Sanada, Hironobu, Yatabe, Midori Sasaki, Hashimoto, Shigeatsu, Yoneda, Minoru, Felder, Robin A., Jose, Pedro A., Watanabe, Tsuyoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067119/
https://ncbi.nlm.nih.gov/pubmed/19261744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00580.2007
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