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Angiotensin II type 1 receptor blocker attenuates the activation of ERK and NADPH oxidase by mechanical strain in mesangial cells in the absence of angiotensin II

It has been reported that mechanical strain activates extracellular signal-regulated protein kinases (ERK) without the involvement of angiotensin II (Ang II) in cardiomyocytes. We examined the effects of mechanical strain on ERK phosphorylation levels in the absence of Ang II using rat mesangial cel...

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Detalhes bibliográficos
Main Authors: Yatabe, Junichi, Sanada, Hironobu, Yatabe, Midori Sasaki, Hashimoto, Shigeatsu, Yoneda, Minoru, Felder, Robin A., Jose, Pedro A., Watanabe, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067119/
https://ncbi.nlm.nih.gov/pubmed/19261744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00580.2007
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