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The viral context instructs the redundancy of costimulatory pathways in driving CD8(+) T cell expansion
Signals delivered by costimulatory molecules are implicated in driving T cell expansion. The requirements for these signals, however, vary from dispensable to essential in different infections. We examined the underlying mechanisms of this differential T cell costimulation dependence and found that...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4558566/ https://ncbi.nlm.nih.gov/pubmed/26263500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07486 |
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