The Breadth of Synthetic Long Peptide Vaccine-Induced CD8(+) T Cell Responses Determines the Efficacy against Mouse Cytomegalovirus Infection

There is an ultimate need for efficacious vaccines against human cytomegalovirus (HCMV), which causes severe morbidity and mortality among neonates and immunocompromised individuals. In this study we explored synthetic long peptide (SLP) vaccination as a platform modality to protect against mouse CM...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Panagioti, Eleni, Redeker, Anke, van Duikeren, Suzanne, Franken, Kees LMC, Drijfhout, Jan Wouter, van der Burg, Sjoerd H., Arens, Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026341/
https://ncbi.nlm.nih.gov/pubmed/27637068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005895
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