The Breadth of Synthetic Long Peptide Vaccine-Induced CD8(+) T Cell Responses Determines the Efficacy against Mouse Cytomegalovirus Infection

There is an ultimate need for efficacious vaccines against human cytomegalovirus (HCMV), which causes severe morbidity and mortality among neonates and immunocompromised individuals. In this study we explored synthetic long peptide (SLP) vaccination as a platform modality to protect against mouse CM...

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Опубликовано в: :PLoS Pathog
Главные авторы: Panagioti, Eleni, Redeker, Anke, van Duikeren, Suzanne, Franken, Kees LMC, Drijfhout, Jan Wouter, van der Burg, Sjoerd H., Arens, Ramon
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026341/
https://ncbi.nlm.nih.gov/pubmed/27637068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005895
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