The Breadth of Synthetic Long Peptide Vaccine-Induced CD8(+) T Cell Responses Determines the Efficacy against Mouse Cytomegalovirus Infection

There is an ultimate need for efficacious vaccines against human cytomegalovirus (HCMV), which causes severe morbidity and mortality among neonates and immunocompromised individuals. In this study we explored synthetic long peptide (SLP) vaccination as a platform modality to protect against mouse CM...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Panagioti, Eleni, Redeker, Anke, van Duikeren, Suzanne, Franken, Kees LMC, Drijfhout, Jan Wouter, van der Burg, Sjoerd H., Arens, Ramon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5026341/
https://ncbi.nlm.nih.gov/pubmed/27637068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005895
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