Interleukin‐6‐mediated resistance to immunotherapy is linked to impaired myeloid cell function

High serum levels of interleukin‐6 (IL‐6) correlate with poor prognosis and chemotherapy resistance in several cancers. The underlying mechanisms and its effects on immunotherapy are largely unknown. To address this, we developed a human papillomavirus type 16 (HPV16)‐associated tumor model expressi...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Beyranvand Nejad, Elham, Labrie, Camilla, van der Sluis, Tetje C., van Duikeren, Suzanne, Franken, Kees L. M. C., Roosenhoff, Rueshandra, Arens, Ramon, van Hall, Thorbald, van der Burg, Sjoerd H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Tumor Immunology and Microenvironment
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693233/
https://ncbi.nlm.nih.gov/pubmed/32875568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.33280
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