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Local immunomodulation for cancer therapy: Providing treatment where needed
In murine models of cancer, we have achieved efficient systemic activation of tumor-specific T cells by the local administration of a CTLA4-blocking antibody at low doses. Using a slow-release formulation, we could drastically lower the serum levels of the antibody, hence decreasing adverse effects...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3897564/ https://ncbi.nlm.nih.gov/pubmed/24490127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26493 |
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