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Mechanisms of Islet Amyloidosis Toxicity in Type 2 Diabetes
Amyloid formation by the neuropancreatic hormone, islet amyloid polypeptide (IAPP or amylin), one of the most amyloidogenic sequences known, leads to islet amyloidosis in type 2 diabetes and to islet transplant failure. Under normal conditions, IAPP plays a role in the maintenance of energy homeosta...
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| Gepubliceerd in: | FEBS Lett |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4557799/ https://ncbi.nlm.nih.gov/pubmed/23337872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.01.017 |
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