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The CD27(+) memory B cells display changes in the gene expression pattern in elderly individuals

Memory B cells (MBCs) have a long lifespan compared with naive B cells (NBCs), remaining viable for years. This could predispose them to suffer misbalances in the gene expression pattern in the long term, which might be involved in the development of age-related B-cell disorders. In order to identif...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Báez, Alicia, Álvarez-Laderas, Isabel, Piruat, José I, Caballero-Velázquez, Teresa, Barbado, María Victoria, Millán-Uclés, África, Medrano, Mayte, García-Guerrero, Estefanía, Sánchez-Abarca, Luis Ignacio, Pérez-Simón, José Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557676/
https://ncbi.nlm.nih.gov/pubmed/25196729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12381
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